课题组简介：

于彦春，男，1973年生，教授、博导、杭州师范大学生命与环境科学学院副院长，浙江省“高层次人才特殊支持计划”科技创新领军人、浙江省“钱江学者”特聘教授、浙江省“151”一层次人才、浙江省高校中青年学科带头人、杭州市“521”人才，现任浙江省遗传学会理事。

主要从事水稻抗逆遗传、株型调控和信号转导等领域研究，承担国家重点研究计划、国家自然科学基金重大研究计划和面上项目以及浙江省自然科学基金项目等省部级以上科研项目10余项。在水稻抗逆及株型调控分子机理等领域取得了一系列创新性研究成果。在Nature、Nat Struct &Mol Biol、Plant Cell，PNAS，Nature Communication, Plant Journal, Cell Research, New Phytologist等刊物上发表学术论文20多篇，授权国家发明专利5项、培育国审品种1份。

课题组照片

课题组负责人：于彦春

课题组成员

教师：武丽敏、陈飞、 阮班普

学生：周鑫媛、周梦浩、侯纯朴、吴辉、姚丽璇、刘玉玉、乔瑜、 王明扬、唐明月、吕宣彤、赵旭南  

主要研究方向

于彦春团队主要以水稻为材料，辅以拟南芥，通过遗传学、生物化学、细胞生物学及组学等手段，开展水稻非生物环境胁迫、光信号转导和产量性状分子机制研究。主要研究内容：

1.     水稻非生物环境胁迫方面

课题组通过EMS诱变筛选，获得大量温度和盐响应改变突变体，利用图位克隆，多个基因已被克隆，部分研究内容已发表。

2.     光信号转导方面

阳光是水稻光合作用的能量来源，是决定水稻产量最重要的因素之一。水稻90%以上的干重直接来源于光合作用。了解光信号转导和光合作用的生物学过程和遗传基础是培育高光效水稻品种的前提。叶绿体移动是植物适应光环境改变而形成的自我保护，其分子调控机理已在拟南芥中被广泛研究，已鉴定了包括光受体在内的多个因子。但对水稻而言，虽然其基因组含有光受体基因座，但是前人研究结果却发现其并不表现出叶绿体移动特性。因此从分子水平上揭示水稻叶绿体适应光环境的遗传基础和调控网络，将对深入理解水稻光信号转导的生物学机理具有重要的科学意义。团队首次在水稻中建立了光刺激下观察叶绿体移动方法，并利用这些方法开展了水稻叶绿体移动突变体筛选工作。

3.     激素与水稻株型和粒型

水稻株型与穗型是影响水稻产量的重要因子，这两个性状与激素密切相关。通过对植物激素合成与信号途径突变体的分离鉴定及其相应基因的克隆，深入了解植物激素的合成、运输、信号转导和降解及其在水稻株型粒型形成中的作用，全面深入地了解这些调控途径及其分子机制将帮助人们更好地理解激素如何在植物生长发育中发挥作用。

代表性成果：

1. Banpu Ruan, Hui Wu, Yaohuang Jiang, Jiehua Qiu , Fei Chen, Yanli Zhang, Yu Qiao, Mingyue Tang, Yingying Ma, Qian Qian^2*, Limin Wu^1* and Yanchun Yu^*. SPL50 Regulates Cell Death and Resistance to Magnaporthe Oryzae in Rice.Rice, 2024 17:51.（中科院1区，共同通讯作者）

2. Yanli Zhang, Guojun Dong, Ying Zhang, Yaohuang Jiang, Fei Chen, Banpu Ruan, Limin Wu,* and Yanchun Yu*. BLA1 Affects Leaf Angles by Altering Brassinosteroid Biosynthesis in Rice (Oryza sativa L.),J Agric. Food Chem, 2024,72: 19629−19643.（中科院1区，共同通讯作者）

3. Yanli Zhang^#, Guojun Dong^#, Limin Wu^#, Xuewen Wang, Fei Chen, Erhui Xiong, Guosheng Xiong, Yihua Zhou, Zhaosheng Kong, Ying Fu, Dali Zeng, Dianrong Ma, Qian Qian*, Yanchun Yu*. Formin protein DRT1 affects gross morphology and chloroplast relocation in rice. Plant Physiol, 2023,191(1):280-298（中科院1区，共同通讯作者）.

4. Yanli Zhang ^#, Guojun Dong ^#, Fei Chen, Erhui Xiong, Huijie Liu, Yaohuang Jiang, Guosheng Xiong, Banpu Ruan, Qian Qian, Dali Zeng, Dianrong Ma, Yanchun Yu *, Limin Wu*.The kinesin‑13 protein BR HYPERSENSITIVE 1 is a negative brassinosteroid signaling component regulating rice growth and development.Theor Appl Genet,2022,135(5):1751-1766.（中科院1区，共同通讯作者）.

5. Fei Chen ^#, Guojun Dong ^#, Fang Wang, Yingqi Shi, Jiayu Zhu, Yanli Zhang, Banpu Ruan, Yepin Wu, Xue Feng, Chenchen Zhao, Miing T Yong, Paul Holford, Dali Zeng, Qian Qian, Limin Wu, Zhong-Hua Chen *, Yanchun Yu* .A β-ketoacyl carrier protein reductase confers heat tolerance via the regulation of fatty acid biosynthesis and stress signaling in rice，New Phytologist,2021,232(2): 655–672(中科院1区，共同通讯作者).

6. Erhui Xiong ^#, Guojun Dong ^# , Fei Chen ^#, Chen Zhang, Shan Li, Yanli Zhang, Jahidul Islam Shohag, Xiaoe Yang, Yihua Zhou, Qian Qian, Limin Wu *, Yanchun Yu*.Formyl tetrahydrofolate deformylase affects hydrogen peroxide accumulation and leaf senescence by regulating the folate status and redox homeostasis in rice,Sci China Life Sci,2021,64(5):720-738(中科院1区，共同通讯作者).

6.Erhui Xiong, Chen Zhang, Chenxi Ye, Yaohuang Jiang, Yanli Zhang, Fei Chen, Guojun Dong, Dali Zeng, Yanchun Yu*, Limin Wu*.iTRAQ-based proteomic analysis provides insights into the molecular mechanisms of rice formyl tetrahydrofolate deformylase,Planta, 2021,254(4): 66-76(中科院2区，共同通讯作者).

7.Fei Chen, Guojun Dong, Xiaohui Ma, Fang Wang, Yanli Zhang, Erhui Xiong , Jiahuan Wu, Huizhong Wang, Qian Qian, Limin Wu *, Yanchun Yu *. UMP kinase activity is involved in proper chloroplast development in rice. Photosynthesis Research, 2018, 137(1):53-67(中科院2区，共同通讯作者).

8.Fei Chen, Guojun Dong, Limin Wu, Fang Wang, Xingzheng Yang, Xiaohui Ma, Haili Wang, Jiahuan Wu, Yanli Zhang, Huizhong Wang, Qian Qian*, Yanchun Yu*.A Nucleus-Encoded Chloroplast Protein YL1 Is Involved in Chloroplast Development and Efficient Biogenesis of Chloroplast ATP Synthase in Rice. Sci Reports, 2016, 2;6:32295. doi: 10.1038/srep32295(中科院2区，共同通讯作者).

9.Cao Xu^#, Yonghong Wang^#, Yanchun Yu^#, Jingbo Duan, Zhigang Liao, Guosheng Xiong, Xiangbin Meng, Guifu Liu, Qian Qian, Jiayang Li. Degradation of MOC1 by the anaphase-promoting complex regulates rice tillering. Nat. Commun, 2012 (3):750 doi: 10.1038/ ncomms1743. (中科院1区，共同第一作者)

10.Lin Guo^#, Yanchun Yu^#, J.A. Law and Xiaoyu Zhang. SET DOMAIN GROUP2 is the major histone H3 lysine 4 trimethyltransferase in Arabidopsis. Proc Natl Acad Sci USA, 2010,107 (43): 18557-18562 (中科院1区，共同第一作者)

11.Mu Zhang^#, Baocai Zhang^#, Qian Qian^#, Yanchun Yu^#, Rui Li, Junwen Zhang, Xiangling Liu, Dali Zeng Jiayang Li and Yihua Zhou. Brittle Culm 12, a dual-targeting kinesin-4 protein, controls cell-cycle progression and wall properties in rice. Plant J, 2010, 63: 312-328. (中科院1区，共同第一)

12.Ramakrishna K Chodavarapu 1 , Suhua Feng, Yana V Bernatavichute, Pao-Yang Chen, Hume Stroud, Yanchun Yu, Jonathan A Hetzel, Frank Kuo, Jin Kim, Shawn J Cokus, David Casero, Maria Bernal, Peter Huijser, Amander T Clark, Ute Krämer, Sabeeha S Merchant, Xiaoyu Zhang, Steven E Jacobsen, Matteo Pellegrini. Relationship between nucleosome positioning and DNA methylation. Nature, 2010, 466: 388-392.

13. Celina Costas, Maria de la Paz Sanchez, Hume Stroud, Yanchun Yu, Juan Carlos Oliveros, Suhua Feng, Alberto Benguria, Irene López-Vidriero, Xiaoyu Zhang, Roberto Solano, Steven E Jacobsen, Crisanto Gutierrez. Genome-wide identification of Arabidopsis origins of DNA replication and their associated epigenetic signatures. Nat Struct Mol Biol. 2011,18(3):395–400.

14. Guangyan Xiong, Rui Li, Qian Qian, Xueqin Song, Xiangling Liu, Yanchun Yu, Dali Zeng, Jianmin Wan, Jiayang Li, Yihua Zhou. The rice dynamin-related protein DRP2B mediates membrane trafficking and thereby plays a critical role in secondary cell wall cellulose biosynthesis. Plant J, 2010, 64(1):56-70.

15. Yanchun Yu^#, Tian Tang^#, Qian, Qian^#, Yonghong Wang, Meixian Yan, Dali Zeng, Bin Han, Chong I Wu, Shuhua Shi, Jiayang Li. Independent losses of function in a polyphenol oxidase in rice: differentiation in grain discoloration between subspecies and the role of positive selection under domestication. Plant Cell, 2008, 20: 2946-2959. (#共同第一)