动物学

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高建芳

来源 : 生科院     作者 :       时间 : 2015-03-25     点击 : 2990

高建芳,男,博士,副研究员,中国动物学会两栖爬行动物学分会理事,杭州市131人才培养计划三层次人选。主要研究兴趣:揭示生物毒素的组成,探讨各毒素组分的系统进化与变异的成因;研究特定毒素组分结构与功能的调控机制。以第一作者或合作作者在Journal of ProteomicsToxiconJournal of Immunological Methods等期刊上发表与蛇毒蛋白组构成和功能的种内种间变异、蛇毒适应和鉴别应用以及爬行类生活史进化相关的论文21 篇,其中SCI 论文17 篇;申报与蛇类研究相关专利4 项,其中2 项已授权;主持国家自然科学基金项目3项、省部级自然科学基金项目和重点研发计划项目各1项。


学习工作经历:

2001.9-2005.6 杭州师范大学 学士学位

2005.9-2010.6 南京师范大学生态学 博士学位

2010.7-2013.9 杭州师范大学 助理研究员

2013.9至今  杭州师范大学 副研究员

 E-mailgaojf308@163.com

5年主持在研项目:

[1]     基于代价与效益分析探讨短尾蝮定量注毒行为的进化成因,国家自然科学基金面上项目,31770428,直接经费56万,2018.1-2021.12(主持)

[2]     亚洲蝮属蛇毒蛋白组种间变异的系统发育信号与食性选择作用,国家自然科学基金面上项目,3147199584万,2015.1-2018.12(主持)

[3]     食性和猎物抗性驱动的舟山眼镜蛇毒地理变异,国家自然科学基金青年项目,3110163523万,2012.1-2014.12(主持)

[4]     多组学串联技术筛选两种海蛇毒腺新药用转录本及辅助制备抗蛇毒血清,海南省重点研发计划项目,ZDYF201812050万,2018.1-2019.12(合作单位主持人)

[5]     磷酸化修饰对短尾蝮蛇毒蛋白组结构与活性的调控,浙江省自然科学基金,LY14C0300079.5万,2014.1-2016.12(主持)

[6]     五步蛇毒腺细胞培养及泌毒关键技术研究,杭州市科技计划项目,20180533B0410万,2018-2019(主持)


主要发表论文目录(*通讯作者):

[1]     Xu N, Zhao HY, Yin Y, Shen SS, Shan LL, Chen CX, Zhang YX, Gao JF, Ji X. Combined venomics, antivenomics and venom gland transcriptome analysis of the monocoled cobra (Naja kaouthia) from China. Journal of Proteomics 2017, 159, 19–31.

[2]     Wu YQ, Qu YF, Wang XJ, Gao JF, Ji X. Does the oviparity-viviparity transition alter the partitioning of yolk in embryonic snakes? BMC Evolutionary Biology 2017, 17, 235.

[3]     Shan LL, Gao JF*, Zhang YX, Shen SS, He Y, Wang J, Ma XM, Ji X*. Proteomic characterization and comparison of venoms from two elapid snakes (Bungarus multicinctus and Naja atra) from China. Journal of Proteomics 2016, 138, 83–94.

[4]     Gao JF, Wang J, He Y, Qu YF, Lin LH, Mao XM, Ji X. Proteomic and biochemical analyses of short-tailed pit viper (Gloydius brevicaudus) venom: age-related variation and composition-activity correlation. Journal of Proteomics 2014, 105, 307–322.

[5]     He Y, Gao JF, Lin LH, Ma XM, Ji X. Age-related variation in snake venom: evidence from two snakes (Naja atra and Deinagkistrodon acutus) in southeastern China. Asian Herpetological Research 2014, 5, 119-127.

[6]     Lin LH, Hua, L, Qu YF, Gao JF, Ji X. The phylogeographical pattern and conservation of the Chinese cobra (Naja atra) across its range based on mitochondrial control region sequence. PLoS ONE 2014, 9, e106944.

[7]     Gao JF, Qu YF, Zhang XQ, He Y, Ji X. Neonate-to-adult transition of snake venomics in the short-tailed pit viper, Gloydius brevicaudus. Journal of Proteomics 2013, 84, 148–157.

[8]     Gao JF, Wang J, Qu YF, Ma XM, Ji X. Immunoreactivity between venoms and commercial antiserums in four Chinese snakes and venom identification by species-specific antibody. Journal of Immunological Methods 2013, 387, 211–218.

[9]     Hua L, Mao LX, Chen C, Gao JF, Lin LH. Isolation and characterization of microsatellite loci in the Reevese’s butterfly lizard Leiolepis reevesii (Agamidae). Conservation Genetics Resources 2012, 4, 791–794.

[10] Gao JF, Qu YF, Zhang XQ, Ji X. Within-clutch variation in venoms from hatchlings of Deinagkistrodon acutus (Viperidae). Toxicon 2011, 57, 970–977.

[11] Gao JF, Qu YF, Luo LG, Ji X. Evolution of reptilian viviparity: a test of the maternal manipulation hypothesis in a temperate snake, Gloydius brevicaudus (Viperidae). Zoological Science 2010, 27, 248–255.

[12] Lu HL, Gao JF, Ma XH, Lin ZH, Ji X. Tail loss affects fecundity but not offspring traits in the Chinese skink Eumeces chinensis. Current Zoology 2012, 58, 228–235.

[13] Qu YF, Gao JF, Mao LX, Ji X. Sexual dimorphism and female reproduction in two sympatric toad-headed lizards, Phrynocephalus frontalis and P. versicolor (Agamidae). Animal Biology 2011, 61, 139–151.

[14] Qu YF, Li H, Gao JF, Ji X. Embryonic thermosensitivity and hatchling morphology differ between two coexisting lizards. Acta Oecologica 2011, 37, 375–380.

[15] Qu YF, Li H, Gao JF, Ji X. Geographic variation in reproductive traits and trade-offs between size and number of eggs in the king ratsnake, Elaphe carinata. Biological Journal of the Linnean Society 2011, 104, 701–709.

[16] Qu YF, Li H, Gao JF, Xu XF, Ji X. Thermal preference, thermal tolerance and the thermal dependence of digestive performance in two Phrynocephalus lizards (Agamidae), with a review of species studied. Current Zoology 2011, 57, 684–700.



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