谭舟，男

国籍：中国

出生日期：1982.3.13

学习工作经历

2001-2005 中南大学 （生物工程）                                  学士学位

2005-2010 浙江大学 （细胞生物学专业）                     博士学位

2013-2015美国斯坦福大学（转化医学）                      博士后

2010至今 杭州师范大学（生命与环境科学学院）       副教授

专业与研究领域

神经细胞生物学，主要专注于综合分子生物学、细胞生物学与生物信息学的相关技术应用于神经系统疾病的诊疗，重点关注中枢神经系统疾病如阿尔兹海默症、肌萎缩侧索硬化症、帕金森病与胶质瘤的早期诊断与干预治疗。擅长分子靶点的筛选与分析以及检测抗体的开发与改造，博后期间曾兼职美国mProbe公司高级研发顾问，负责公司儿童川崎病早产诊断产品的开发与应用。回国后曾兼职杭州云检医学科技与浙江欧塞思生物科技公司研发顾问，主要负责诊断试剂的研发与生产。

承担科研项目

学术兼职及荣誉：

浙江省分析测试协会细胞生物与生化分析专业委员会常务委员。

入选杭州市留学回国人才计划重点项目。

广东省自然科技学基金评审专家。

专业期刊Neuroscience Bulletin, JGG, Mol Neurobiology, NRR等多个国内外期刊审稿人。

部分已发表论文列表：

1. Role of Gltp in Maturation of Oligodendrocytes Under the Regulation of Nkx2.2. Zhang C, Chen Z, Zhang D, Wang X, Qiu M, Tan Z. Mol Neurobiol. 2023 Sep;60(9):4897-4908.

2. CircXPO1 Promotes Glioblastoma Malignancy by Sponging miR-7-5p. Wang X, Wang J, An Z, Yang A, Qiu M, Tan Z. Cells. 2023 Mar 8;12(6):831.

3. Aberrant nuclear lamina contributes to the malignancy of human gliomas. Pei S, Wang X, Wang X, Huang H, Tao H, Xie B, Yang A, Qiu M, Tan Z. J Genet Genomics. 2022 Feb;49(2):132-144.

4. TPGS-1000 exhibits potent anticancer activity for hepatocellular carcinoma in vitro and in vivo.

Chen Y, Mo L, Wang X, Chen B, Hua Y, Gong L, Yang F, Li Y, Chen F, Zhu G, Ni W, Zhang C, Cheng Y, Luo Y, Shi J, Qiu M, Wu S, Tan Z, Wang K. Aging (Albany NY). 2020 Jan 27;12(2):1624-1642.

5. Evolutionary genomics analysis of human nucleus-encoded mitochondrial genes: implications for the roles of energy production and metabolic pathways in the pathogenesis and pathophysiology of demyelinating diseases. Shen Y, Wang X, Guo S, Qiu M, Hou G, Tan Z. Neurosci Lett. 2020 Jan 10;715:134600.

6. Repression of Septin9 and Septin2 suppresses tumor growth of human glioblastoma cells.

Xu D, Liu A, Wang X, Chen Y, Shen Y, Tan Z, Qiu M. Cell Death Dis. 2018 May 1;9(5):514.

7. P53 Promotes Retinoid Acid-induced Smooth Muscle Cell Differentiation by Targeting Myocardin. Tan Z, Li J, Zhang X, Yang X, Zhang Z, Yin KJ, Huang H. Stem Cells Dev. 2018 Apr 15;27(8):534-544.

8. Identifying suitable reference genes for developing and injured mouse CNS tissues. Xu D, Liu A, Wang X, Zhang M, Zhang Z, Tan Z, Qiu M. Dev Neurobiol. 2018 Jan;78(1):39-50.

9. A Classification Tool for Differentiation of Kawasaki Disease from Other Febrile Illnesses. Hao S, Jin B, Tan Z, Li Z, Ji J, Hu G, Wang Y, Deng X, Kanegaye JT, Tremoulet AH, Burns JC, Cohen HJ, Ling XB; Pediatric Emergency Medicine Kawasaki Disease Research Group. J Pediatr. 2016 Sep;176:114-120.e8.

10. Urinary Colorimetric Sensor Array and Algorithm to Distinguish Kawasaki Disease from Other Febrile Illnesses. Li Z, Tan Z, Hao S, Jin B, Deng X, Hu G, Liu X, Zhang J, Jin H, Huang M, Kanegaye JT, Tremoulet AH, Burns JC, Wu J, Cohen HJ, Ling XB; Emergency Medicine Kawasaki Disease Research Group. PLoS One. 2016 Feb 9;11(2):e0146733.

11. Developmental expression and function analysis of protein tyrosine phosphatase receptor type D in oligodendrocyte myelination. Zhu Q, Tan Z, Zhao S, Huang H, Zhao X, Hu X, Zhang Y, Sheilds CB, Uetani N, Qiu M. Neuroscience. 2015 Nov 12:308:106-14.

12. Serological targeted analysis of an ITIH4 peptide isoform: a preterm birth biomarker and its associated SNP implications. Tan Z, Hu Z, Cai EY, Alev C, Yang T, Li Z, Sung J, El-Sayed YY, Shaw GM, Stevenson DK, Butte AJ, Sheng G, Sylvester KG, Cohen HJ, Ling XB. J Genet Genomics. 2015 Sep 20;42(9):507-10.

13. Cerebrospinal fluid protein dynamic driver network: At the crossroads of brain tumorigenesis.

Tan Z, Liu R, Zheng L, Hao S, Fu C, Li Z, Deng X, Jang T, Merchant M, Whitin JC, Guo M, Cohen HJ, Recht L, Ling XB. Methods. 2015 Jul 15;83:36-43.

14. Mesenchymal-like progenitors derived from human embryonic stem cells promote recovery from acute kidney injury via paracrine actions. Luo J, Zhao X, Tan Z, Su Z, Meng F, Zhang M. Cytotherapy. 2013 Jun;15(6):649-62.

15. Derivation of multipotent nestin(+)/CD271 (-)/STRO-1 (-) mesenchymal-like precursors from human embryonic stem cells in chemically defined conditions. Wu R, Gu B, Zhao X, Tan Z, Chen L, Zhu J, Zhang M. Hum Cell. 2013 Mar;26(1):19-27.

16. Proteomic analyses reveal common promiscuous patterns of cell surface proteins on human embryonic stem cells and sperms. Gu B, Zhang J, Wu Y, Zhang X, Tan Z, Lin Y, Huang X, Chen L, Yao K, Zhang M. PLoS One. 2011 May 3;6(5):e19386.

17. Immunomodulative effects of mesenchymal stem cells derived from human embryonic stem cells in vivo and in vitro. Tan Z, Su ZY, Wu RR, Gu B, Liu YK, Zhao XL, Zhang M. J Zhejiang Univ Sci B. 2011 Jan;12(1):18-27.

18. Production of rabbit monoclonal antibodies against mouse embryonic stem cells and identification of pluripotency-associated surface antigens. Tan Z, Zhang J, Su Z, Gu B, Jiang X, Luo J, Ji H, Wang G, Tao B, Zhao X, Chen L, Yu G, Zhu W, Zhang M. J Immunol Methods. 2011 Feb 28;365(1-2):149-57.

19. In vitro assessing the risk of drug-induced cardiotoxicity by embryonic stem cell-based biosensor. Liu Q, Yu H, Tan Z, Cai H, Ye W, Zhang M, Wang P. Sensors and Actuators B: Chemical. 2011 155 (2011) 214–219.

20. Derivation, characterization and differentiation of a new human embryonic stem cell line from a Chinese hatched blastocyst assisted by a non-contact laser system. Wu R, Xu C, Jin F, Tan Z, Gu B, Chen L, Yao X, Zhang M. Hum Cell. 2010 Aug;23(3):89-102.

21. Generation and characterisation of rabbit monoclonal antibodies against the native cell surface antigens of embryonic stem cells. Lu Y, Su Z, Li Y, Luo J, Tan Z, Ji H, Zhu W, Yu G, Chen L, Zhang M. J Genet Genomics. 2010 Jul;37(7):483-92.

22. Promotion of self-renewal of embryonic stem cells by midkine. Yao X, Tan Z, Gu B, Wu RR, Liu YK, Dai LC, Zhang M. Acta Pharmacol Sin. 2010 May;31(5):629-37.

23. Early homing behavior of Stro-1- mesenchyme-like cells derived from human embryonic stem cells in an immunocompetent xenogeneic animal model. Su Z, Wu R, Tan Z, Li Y, Chen L, Luo J, Zhang M. Biochem Biophys Res Commun. 2010 Apr 9;394(3):616-22.

24. Effect of crystallinity of calcium phosphate nanoparticles on adhesion, proliferation, and differentiation of bone marrow mesenchymal stem cells. Hu Q, Tan Z, Liu Y, Tao J, Cai Y, Zhang M, Pan H, Xu X, Tang R. J. Mater. Chem. 2007, 17, 4690–4698

已授权第一发明人专利列表：

1.一种septin基因shRNA在制备septin基因活性抑制剂中的应用 ZL201810283342.7

2. 一种敲低circXPO1的抑制剂及其在制备治疗胶质瘤药物中的应用ZL202210406260.3

3. 一种新型髓鞘染色试剂盒及其染色方法 ZL202210902654.8

4. 一种改进型髓鞘染色试剂盒及其染色方法 ZL202211136504.7

5. 银杏内酯B在制备胶质瘤细胞活性抑制剂中的应用 ZL201911013105. X