课题组简介：动物磁感应与生物导航团队聚焦动物感知微弱地磁场实现长距离导航与精准定位的机制，开展从宏观动物行为到微观量子生物学机制的跨尺度、多物种研究，同时也致力于磁遗传学/生物磁控技术开发与量子生物学前沿拓展。

课题组负责人：谢灿

课题组成员

教师：谢灿、孔得鑫

学生：高晓静、张文蕊、马沪宁、颜丙鑫     

主要研究方向

1. 动物磁感应与生物导航原理；

2. 磁遗传学与生物磁控技术；

3. 量子生物学前沿拓展。

代表性成果：

1. Siying Qin#, Hang Yin#, Celi Yang, Yunfeng Dou, Zhongmin Liu, Peng Zhang, He Yu, Yulong Huang, Jing Feng, Junfeng Hao, Jia Hao, Lizong Deng, Xiyun Yan, Xiaoli Dong, Zhongxian Zhao, Taijiao Jiang, Hong-Wei Wang, Shu-Jin Luo and Can Xie*, A magnetic protein biocompass. Nature Materials, 15(2): 217-226 (2016).

2. Jingjing Xu, Lauren E. Jarocha, Tilo Zollitsch, Marcin Konowalczyk, Kevin B. Henbest, Sabine Richert, Matthew J. Golesworthy, Jessica Schmidt, Victoire Déjean, Daniel J. C. Sowood, Marco Bassetto, Jiate Luo, Jessica R. Walton, Jessica Fleming, Yujing Wei, Tommy L. Pitcher, Gabriel Moise, Maike Herrmann, Hang Yin, Haijia Wu, Rabea Bartölke, Stefanie J. Käsehagen, Simon Horst, Glen Dautaj, Patrick D. F. Murton, Angela S. Gehrckens, Yogarany Chelliah, Joseph S. Takahashi, Karl-Wilhelm Koch, Stefan Weber, Ilia A. Solov’yov*, Can Xie*, Stuart R. Mackenzie*, Christiane R. Timmel*, Henrik Mouritsen* & Peter J. Hore*, Magnetic sensitivity of cryptochrome 4 from a migratory songbird, Nature, 594(7864): 535-540 (2021) (Cover Story, 封面长文，共同通讯作者)

3. Can Xie*, Searching for unity in diversity of animal magnetoreception: from biology to quantum mechanics and back. The Innovation, 3(3): 293-295, (2022).

4. Zhe Guan#, Tiantian Cai#, Zhongmin Liu, Yunfeng Dou, Xuesong Hu, Peng Zhang, Xin Sun, Hongwei Li, Yao Kuang, Qiran Zhai, Hao Ruan, Xuanxuan Li, Zeyang Li, Qihui Zhu, Jingeng Mai, Qining Wang, Luhua Lai, Jianguo Ji, Haiguang Liu, Bin Xia, Taijiao Jiang, Shu-Jin Luo, Hongwei Wang, Can Xie*, Origin of the reflectin gene and hierarchical assembly of its protein. Current Biology, 27, 2833–2842, (2017). (Cover Story, 封面长文)

5. Zhen Guo, Shuai Xu, Xue Chen, Changhao Wang, Peilin Yang, Siying Qin, Cuiping Zhao, Fan Fei, Xianglong Zhao, Ping-Heng Tan, Junfeng Wang & Can Xie*, Modulation of MagR magnetic properties via iron–sulfur cluster binding. Scientific Reports, 11, 23941 (2021).

6. Xuehui Chen#, Huiwen Yan#, Dan Liu, Qingji Xu, Hongxia Duan, Jing Feng*, Xiyun Yan* & Can Xie*, Structure Basis for AA98 Inhibition on the Activation of Endothelial Cells Mediated by CD146. iScience, 24(5): 102417 (2021)

7. Peilin Yang, Tiantian Cai, Lei Zhang, Daqi Yu, Zhen Guo, Yuebin Zhang, Guohui Li, Xin Zhang*, and Can Xie*, A Rationally Designed Building Block of the Putative Magnetoreceptor MagR. Bioelectromagnetics, 43(5):317-326,(2022).

8. Yajie Zhou, Tianyang Tong, Mengke Wei, Peng Zhang, Fan Fei, Xiujuan Zhou, Zhen Guo, Jing Zhang, Huangtao Xu, Lei Zhang, Shun Wang, Junfeng Wang, Tiantian Cai, Xin Zhang, Can Xie*. Towards magnetism in pigeon MagR: Iron- and iron-sulfur binding work indispensably and synergistically. Zoological Research, 44(1): 142-152, (2023). (Cover Story 封面长文)

9. Jing Zhang, Yafei Chang, Peng Zhang, Yanqi Zhang, Mengke Wei, Chenyang Han, Shun Wang, Hui-Meng Lu, Tiantian Cai*, Can Xie*. On the evolutionary trail of MagRs. Zoological Research, 45(4): 821-830, (2024).

10. Yanqi Zhang, Peng Zhang, Junjun Wang, Jing Zhang, Tianyang Tong, Xiujuan Zhou, Yajie Zhou, Mengke Wei, Chuanlin Feng, Jinqian Li, Xin Zhang, Can Xie*, Tiantian Cai*. Mitochondrial targeting sequence of magnetoreceptor MagR: More than just targeting. Zoological Research, 45(3): 468-477, (2024).

    更新时间2026年10月