课题组简介：

杜立群教授课题组立足于杭州师范大学生命与环境科学学院植物分子生物学实验室，长期专注于植物钙调素信号转导研究领域，一直倡导将前沿性基础研究成果与国民经济发展和国家重大需求紧密相连。

目前以杜立群教授、皮二旭副教授、曾后清副教授为主的科研课题组，聚焦植物钙调素信号转导机制、大豆等经济作物与微生物共生机制、植物逆境胁迫信号转导等科学问题。课题组负责人杜立群教授是浙江省高等学校“钱江学者”特聘教授，从事植物信号转导分子机理方面的研究，侧重植物细胞钙信号转导、植物逆境胁迫下钙调素的调控作用等，并在植物科学领域取得过突破性进展。

课题组至2012年组建以来，获得国家自然科学基金联合基金重点项目1项，国家自然科学基金青年项目3项，国家自然科学基金面上项目1项，浙江省自然科学基金项目3项，杭州市科研项目4项。课题组申请国家发明专利4项，其中授权发明专利3项；在Molecular & Cellular Proteomics，The Plant Journal和Plant Soil等杂志上发表SCI论文30余篇。

课题组照片

课题组负责人：杜立群

课题组成员

教师：皮二旭、曾后清

学生：李瑞、倪晓丽、李想、王艺昂、王宇华、戴森焕、陈慧颖、晁可欣、吴海诚

主要研究方向

1. 类钙调蛋白介导的信号

2. 钙调蛋白介导的信号传导对植物免疫反应的调节

3. 植物与微生物共生过程中钙/钙调蛋白介导的CCaMK的调控机制

代表性成果

1. Ying Wu; Xiang Li; Jinnan Zhang; Haiqing Zhao; Shaolin Tan; Wanhao Xu; Jiaqi Pan; Fan Yang;Erxu Pi; ERF subfaminly transcription factors and their function in plant responses to abiotic stresses, Frontiers in Plant Science, 2023, 13

2. Houqing Zeng; Haicheng Wu; Guoping Wang; Senhuan Dai; Qiuqing Zhu; Huiying Chen; Keke Yi; Liqun Du L ; Arabidopsis CAMTA3/SR1 is involved in drought stress tolerance and ABA signaling,Plant Science, 2022, 319: 111250

3. Erxu Pi; Jia Xu; Huihui Li; Wei Fan; Chengmin Zhu; Tongyao Zhang; Jiachen Jiang; Litao He; Hongfei Lu; Huizhong Wang; B.W.Poovaiah; Liqun Du L ; Enhanced salt tolerance of rhizobiainoculated soybean correlates with decreased phosphorylation of the transcription factor GmMYB183 and altered flavonoid biosynthesis, Molecular & Cellular Proteomics, 2019, 18(11): 2225-2243

4. Erxu, Pi; Chengmin, Zhu; Wei, Fan; Yingying, Huang; Liqun, Qu; Yangyang, Li; Qinyi, Zhao;Feng, Ding; Lijuan, Qiu; Huizhong, Wang; B.W., Poovaiah; Liqun, Du L ; Quantitative Phosphoproteomic and Metabolomic Analyses Reveal GmMYB173 Optimizes Flavonoid Metabolism in Soybean under Salt Stress, Molecular & Cellular Proteomics, 2018, 17(6): 1209-1224

5. Zeng H*, Zhang X, Zhang X, Pi E, Xiao L, Zhu Y* ; Early transcriptomic response to phosphate deprivation in soybean leaves as revealed by RNA-sequencing. Int. J. Mol. Sci., 2018, 19, 2145

6. Zeng H*, Zhang Y, Zhang X, Pi E, Zhu Y; Analysis of EF-hand proteins in soybean genome suggests their potential roles in environmental and nutritional stress signaling. Frontiers in Plant Science, 2017, 8: 877

7. Zeng H*, Wang G, Zhang Y, Hu X, Pi E, Zhu Y, Wang H, Du L*; Genome-wide identification of phosphate-deficiency-responsive genes in soybean roots by high-throughput sequencing. Plant and Soil, 2016, 398: 207-227

8. Pi Erxu; Qu Liqun; Hu Jianwen; Huang Yingying; Qiu Lijuan; Lu Hongfei; Jiang Bo; Liu Cong; Peng Tingting; Zhao Ying; Wang Huizhong; Tsai Sau Na; Ngai Saiming; Du Liqun D ; Mechanisms of soybean roots’ tolerances to salinity revealed by proteomic and phosphoproteomic comparisons between two cultivars, Molecular & Cellular Proteomics, 2015, 15(1): 266-288

9. Liqun Du L ; Gul S.Ali; Kayla A.Simons; Jingguo Hou; Tianbao Yang; A.S.N.Reddy; B.W.Poovaiah; Ca2+/calmodulin regulates salicylic-acid-mediated plant immunity, Nature, 2009, 457(7233):1154-1158

10. Liqun Du L ; B.W.Poovaiah ; Ca2+/calmodulin is critical for brassinosteroid biosynthesis and plant growth, Nature, 2005, 437(7059): 741-745